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KMID : 0615720110280020143
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Jouranl of Korean Acupuncture and Moxibustion society
2011 Volume.28 No. 2 p.143 ~ p.153
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A Study on the Effect of Herbal-acupuncture with Schizandrae Fructus Solution on Hyperlipidemia in Rats Induced by High Fat Diet
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Lee Sung-Hwan
Lee Hyun
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Abstract
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Objectives : The purpose of this study is to observe the effects of herbal acupuncture with Schizandrae Fructus solution at GB34(Yangneungcheon) on hyperlipidemia in rats.
Methods : In the present study, herbal acupuncture with Schizandrae Fructus solution was administered into hyperlipidemic mice. The author performed several experimental items to analyze the levels of various components and enzymes in serum, liver, as well as the histological changes of liver and aorta.
Results : 1. In the Schizandrae Fructus herbal-acupuncture group, serum total cholesterol and Atherogenic index were significantly decreased, and the ratios of HDL to total cholesterol, and phospholipid to total cholesterol in serum were significantly increased as compared with those of the control group. 2. In the Schizandrae Fructus herbal-acupuncture group, HMG-CoA reductase activity was significantly decreased as compared with those of the control group. 3. Schizandrae Fructus herbal-acupuncture reduced deposit of lipid in the liver tissue.
Conclusions : From the above results, it is suggested that Schizandrae Fructus herbal-acupuncture at GB34 has a therapeutic effect on hyperlipidemia
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KEYWORD
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hyperlipidemia, Schizandrae Fructus herbal-acupuncture, GB34, Yangneungcheon
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